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EPEN-05. TRANSCRIPTIONAL FACTOR-DIRECTED EPIGENETIC REGULATION IN CANCER NEUROSCIENCE OF ZFTA-RELA EPENDYMOMA
ZFTA-RELA (ZR(FUS)) ependymoma is a pediatric brain tumor with dismal 10-year progression free survival rates. Prior studies revealed low somatic mutation load in pediatric ependymoma compared to adult glioma, suggesting that developmental mechanisms play a key role during disease development. Using...
Autores principales: | Chen, Hsiao-Chi, McDonald, Malcolm, Varadharajan, Srinidhi, Sardar, Debosmita, Mack, Stephen C, Deneen, Benjamin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260019/ http://dx.doi.org/10.1093/neuonc/noad073.109 |
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