EPEN-07. A MULTICENTER STUDY OF POOR PROGNOSIS CHROMOSOME 1Q GAIN AND/OR 6Q LOSS IN POSTERIOR FOSSA A EPENDYMOMA SHOWS INCREASED PREVALENCE FROM 20% AT DIAGNOSIS TO 60% AT FIRST RECURRENCE

Ependymoma (EPN) posterior fossa group A (PFA) has the highest rate of recurrence and the worst prognosis of all EPN types. At relapse, it is typically incurable even with re-resection and re-irradiation. The biology of recurrent PFA EPN remains largely unknown, which hinders clinical advances. In t...

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Detalles Bibliográficos
Autores principales: Donson, Andrew, Bertrand, Kelsey, Riemondy, Kent, Gao, Dexiang, Sanford, Bridget, Norris, Gregory, Fu, Rui, Willard, Nicholas, Griesinger, Andrea, Amani, Vladimir, Grimaldo, Enrique, Hankinson, Todd, Booker, Ffyona, Grundy, Richard, Pajtler, Kristian, Ellison, David, Ritzmann, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Ependymoma - EPEN
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260028/
http://dx.doi.org/10.1093/neuonc/noad073.111

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