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XRT-05. LITHIUM PREVENTS RADIATION-INDUCED HIPPOCAMPAL MICROGLIA SENESCENCE IN A MOUSE MODEL OF PEDIATRIC CRANIAL RADIOTHERAPY
Radiotherapy is essential in the treatment of high-grade brain tumors. While often lifesaving, it typically results in long-term complications in 50-96 % of the treated individuals, where cognitive deficits are particularly debilitating, especially in pediatric patients. Although the survival rates...
Autores principales: | Rodrigues, Carlos, Preka, Efthalia, Lastra-Romero, Alejandro, Zisiadis, Georgios Alkis, Zisiadis, Christodoulos, Fragkopoulou, Adamantia, Blomgren, Klas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260030/ http://dx.doi.org/10.1093/neuonc/noad073.301 |
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