Cargando…

METB-08. GENOMIC AND MOLECULAR PROFILING OF PEDIATRIC CENTRAL NERVOUS SYSTEM TUMORS: A SINGLE INSTITUTION ANALYSIS

BACKGROUND: Molecular characterization has revolutionized management of pediatric central nervous system (CNS) tumors, with genomic sequencing for diagnosis and determination of actionable variants now largely considered standard of care. We report a single institution’s experience performing genomi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kline, Cassie, Lin, Fumin, Liou, Angela, Kraya, Adam, Cole, Kristina, Fisher, Michael, Li, Marilyn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Final Category: Genomics/Epigenomics/Metabolomics - METB
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260041/ http://dx.doi.org/10.1093/neuonc/noad073.125

Ejemplares similares

METB-09. GERMLINE PATHOGENIC VARIANTS IN 838 PEDIATRIC BRAIN TUMOR PATIENTS
por: McQuaid, Shelly W, et al.
Publicado: (2023)

METB-12. CLINICAL MONITORING OF MEASURABLE RESIDUAL DISEASE BY CELL-FREE DNA IN PEDIATRIC BRAIN TUMORS
por: Crotty, Erin, et al.
Publicado: (2023)

METB-11. EXPANSION OF THE PEDIATRIC BRAIN TUMOR ATLAS: AN OPEN SCIENCE EFFORT OF CHILDREN’S BRAIN TUMOR NETWORK, KIDS FIRST DATA RESOURCE AND CHILDHOOD CANCER DATA INITIATIVE
por: Koptyra, Mateusz, et al.
Publicado: (2023)

METB-13. A SINGLE-CELL GENETIC IN VIVO LINEAGE-TRACING PLATFORM FOR MEDULLOBLASTOMA
por: Jung, Jangham, et al.
Publicado: (2023)

METB-10. EXPLAINABLE ARTIFICIAL INTELLIGENCE REVEALS DNA METHYLATION PATTERNS UNDERLYING BRAIN TUMOR CLASSIFICATION
por: Benfatto, Salvatore, et al.
Publicado: (2023)

METB-04. THE MOLECULAR CHARACTERIZATION INITIATIVE (MCI): A CLINICAL AND GENOMIC RESOURCE FOR THE PEDIATRIC BRAIN TUMOR COMMUNITY
por: Leary, Sarah, et al.
Publicado: (2023)

METB-02. DECIPHERING THE CELLULAR HETEROGENEITY OF INFANT-TYPE HEMISPHERIC GLIOMAS USING SINGLE-NUCLEI MULTI-OMICS
por: De Micheli, Andrea J, et al.
Publicado: (2023)

METB-01. EXTRACHROMOSOMAL DNA IS ASSOCIATED WITH ONCOGENE AMPLIFICATION AND POOR SURVIVAL ACROSS MULTIPLE PEDIATRIC CANCER TYPES
por: Sridhar, Sunita, et al.
Publicado: (2023)

METB-03. THE DISTINCT GENOMICS OF HIGH-GRADE INFANT GLIOMAS AMONG PEDIATRIC GLIOMAS HARBORING RECEPTOR TYROSINE KINASE FUSIONS
por: de Biagi-Junior, Carlos A O, et al.
Publicado: (2023)

METB-06. HIGH FREQUENCY OF CLINICALLY RELEVANT ALTERATIONS DETECTED BY INTEGRATED TUMOR AND GERMLINE GENE PANEL TESTING IN CHILDREN WITH CNS TUMORS – RESULTS FROM THE TEXAS KIDSCANSEQ STUDY
por: Lin, Frank Y, et al.
Publicado: (2023)

METB-05. NON-INVASIVE DIAGNOSIS OF BRAINSTEM GLIOMAS IN PEDIATRIC, ADOLESCENT, AND YOUNG ADULT PATIENTS THROUGH CEREBROSPINAL FLUID CELL-FREE DNA SEQUENCING
por: Hill, Katherine, et al.
Publicado: (2023)

METB-07. MINIMALLY-INVASIVE DIAGNOSIS OF DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMOR (DLGNT) USING CEREBROSPINAL FLUID CELL-FREE DNA SEQUENCING IN PEDIATRIC AND YOUNG ADULT PATIENTS
por: Larsen, Alexandra Giantini, et al.
Publicado: (2023)

OTHER-08 CONCORDANCE OF INTRAOPERATIVE DIAGNOSIS AND FINAL DIAGNOSIS IN NEUROPATHOLOGY: A SINGLE INSTITUTION EXPERIENCE.
por: Gakinya, Samuel, et al.
Publicado: (2023)

RARE-08. MULTI-INSTITUTIONAL ANALYSIS OF PEDIATRIC RELAPSED/REFRACTORY CENTRAL NERVOUS SYSTEM GERMINOMA
por: McGlynn, Mary Claire, et al.
Publicado: (2023)

OTHER-05 THE CHALLENGES IN MANAGING CHILDREN WITH PRIMARY CENTRAL NERVOUS SYSTEM TUMORS IN UGANDA
por: Katasi, Victoria, et al.
Publicado: (2023)

NEIM-08 MODELING COMPETITION BETWEEN SUBPOPULATIONS WITH VARIABLE DNA CONTENT IN RESOURCE LIMITED MICROENVIRONMENTS
por: Katira, Parag, et al.
Publicado: (2023)

PAX9 Determines Epigenetic State Transition and Cell Fate in Cancer
por: Zhao, Zibo, et al.
Publicado: (2021)

Regulatory Network of PD1 Signaling Is Associated with Prognosis in Glioblastoma Multiforme
por: Lopes-Ramos, Camila M., et al.
Publicado: (2021)

The Ratio of Toxic-to-Nontoxic miRNAs Predicts Platinum Sensitivity in Ovarian Cancer
por: Patel, Monal, et al.
Publicado: (2021)

Gene Fusions Create Partner and Collateral Dependencies Essential to Cancer Cell Survival
por: Gillani, Riaz, et al.
Publicado: (2021)

Clonal Hematopoiesis Mutations in Patients with Lung Cancer Are Associated with Lung Cancer Risk Factors
por: Hong, Wei, et al.
Publicado: (2022)

Association of Genetic Ancestry and Molecular Signatures with Cancer Survival Disparities: A Pan-Cancer Analysis
por: Lee, Kara Keun, et al.
Publicado: (2022)

Gene-Level Germline Contributions to Clinical Risk of Recurrence Scores in Black and White Patients with Breast Cancer
por: Patel, Achal, et al.
Publicado: (2022)

Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma
por: Sen, Arko, et al.
Publicado: (2022)

CRISPR/Cas9-Induced DNA Damage Enriches for Mutations in a p53-Linked Interactome: Implications for CRISPR-Based Therapies
por: Jiang, Long, et al.
Publicado: (2022)

Antisense RNAs Influence Promoter Usage of Their Counterpart Sense Genes in Cancer
por: Bellido Molias, Fernando, et al.
Publicado: (2021)

Comprehensive Analysis of Alternative Splicing in Gastric Cancer Identifies Epithelial–Mesenchymal Transition Subtypes Associated with Survival
por: Jun, Yukyung, et al.
Publicado: (2022)

LncRNA Uc003xsl.1-Mediated Activation of the NFκB/IL8 Axis Promotes Progression of Triple-Negative Breast Cancer
por: Xu, Ying, et al.
Publicado: (2022)

FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits
por: Tsai, Jessica W., et al.
Publicado: (2022)

Efficient Correction of Oncogenic KRAS and TP53 Mutations through CRISPR Base Editing
por: Sayed, Shady, et al.
Publicado: (2022)

Genomic Profiling of Bronchoalveolar Lavage Fluid in Lung Cancer
por: Nair, Viswam S., et al.
Publicado: (2022)

The Prostate Cancer Androgen Receptor Cistrome in African American Men Associates with Upregulation of Lipid Metabolism and Immune Response
por: Berchuck, Jacob E., et al.
Publicado: (2022)

Genetic Ancestry Inference from Cancer-Derived Molecular Data across Genomic and Transcriptomic Platforms
por: Belleau, Pascal, et al.
Publicado: (2023)

Landscape of MicroRNA Regulatory Network Architecture and Functional Rerouting in Cancer
por: Hua, Xu, et al.
Publicado: (2023)

Genetic Determinants of Somatic Selection of Mutational Processes in 3,566 Human Cancers
por: Guo, Jintao, et al.
Publicado: (2021)

Pan-Cancer Analysis of Canonical and Modified miRNAs Enhances the Resolution of the Functional miRNAome in Cancer
por: Distefano, Rosario, et al.
Publicado: (2022)

The 5-Hydroxymethylcytosine Landscape of Prostate Cancer
por: Sjöström, Martin, et al.
Publicado: (2022)

Single-Cell Dissection of the Multiomic Landscape of High-Grade Serous Ovarian Cancer
por: Wang, Yicheng, et al.
Publicado: (2022)

Combinatorial CRISPR/Cas9 Screening Reveals Epistatic Networks of Interacting Tumor Suppressor Genes and Therapeutic Targets in Human Breast Cancer
por: Zhao, Xiaoyu, et al.
Publicado: (2021)

Immunogenetic Determinants of Susceptibility to Head and Neck Cancer in the Million Veteran Program Cohort
por: Liu, Yanhong, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ll9lajqbkekdt4qv00g0ltlqar