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LGG-15. SINGLE-NUCLEUS AND BULK RNA SEQUENCING OF PEDIATRIC PILOCYTIC ASTROCYTOMAS REVEALS CNS LOCATION-ASSOCIATED TUMOR CELL AND MICROENVIRONMENTAL HETEROGENEITY
BACKGROUND: Pilocytic astrocytomas are the most common pediatric central nervous system (CNS) tumors. While the overall survival is generally favorable, a substantial part of the patients relapse, resulting in long-term complications. Additionally, pilocytic astrocytomas show limited genetic heterog...
Autores principales: | Lammers, Julie A S, Rozowsky, Jacob S, Kranendonk, Mariëtte E G, Schouten-van Meeteren, Antoinette Y N, Meijer, Lisethe, Calkoen, Friso G, Hoving, Eelco W, Wesseling, Pieter, van der Lugt, Jasper, Kester, Lennart A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260046/ http://dx.doi.org/10.1093/neuonc/noad073.225 |
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