DIPG-31. HIF-1A AND HIF-2A COMBINATORIAL TARGETING OR HOW TO REVERSE THEIR BALANCED ONCOGENIC IMPACT

HIF-1a and HIF-2a are master regulators operating during tumor hypoxia. Few data are available on their role in pediatric high-grade gliomas (pHGGs), in which recent insights on metabolism and immunotolerance induction through hypoxia-driven mechanisms might opening the path to study further this pr...

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Detalles Bibliográficos
Autores principales: Fuchs, Quentin, Vauchelles, Romain, Cosset, Erika, Gorka, Lucas, Lhermitte, Benoit, Guerin, Eric, Hubsch, Clémence, Foppolo, Sophie, Hibaoui, Youssef, Feki, Anis, Wolf, Thibaut, Dontenwill, Monique, ENTZ-WERLE, Natacha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260072/
http://dx.doi.org/10.1093/neuonc/noad073.078

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260072/
http://dx.doi.org/10.1093/neuonc/noad073.078

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