DIPG-22. TRIPTOLIDE AS A POTENTIALLY PROMISING THERAPY FOR DIFFUSE MIDLINE GLIOMA

Diffuse Midline Gliomas (DMG) are amongst the most lethal pediatric brain tumors. Children diagnosed with DMG face a grim prognosis of 9-11 months from diagnosis. Over 85% of DMG patients harbor mutation affecting histone-encoding genes (H3.1K27M, H3.3K27M) leading to genome hypomethylation and tran...

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Detalles Bibliográficos
Autores principales: Ciani, Ludovica, Laternser, Sandra, Kritzer, Bettina, Hasler, Kerstin, Przystal, Justyna M, Velagapudi, Mohana R, Alonso, Marta M, Zalacain, Marta, Müller, Sabine, Nazarian, Javad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260095/
http://dx.doi.org/10.1093/neuonc/noad073.069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260095/
http://dx.doi.org/10.1093/neuonc/noad073.069

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