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DIPG-22. TRIPTOLIDE AS A POTENTIALLY PROMISING THERAPY FOR DIFFUSE MIDLINE GLIOMA
Diffuse Midline Gliomas (DMG) are amongst the most lethal pediatric brain tumors. Children diagnosed with DMG face a grim prognosis of 9-11 months from diagnosis. Over 85% of DMG patients harbor mutation affecting histone-encoding genes (H3.1K27M, H3.3K27M) leading to genome hypomethylation and tran...
Autores principales: | Ciani, Ludovica, Laternser, Sandra, Kritzer, Bettina, Hasler, Kerstin, Przystal, Justyna M, Velagapudi, Mohana R, Alonso, Marta M, Zalacain, Marta, Müller, Sabine, Nazarian, Javad |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260095/ http://dx.doi.org/10.1093/neuonc/noad073.069 |
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