OTHR-02. CHIMERIC AURORA A KINASE (AURKA) DEGRADERS EFFICIENTLY TARGET N-MYC

MYC family proteins are primary drivers of oncogenic processes in a variety of cancer histologies. N-myc overexpression and amplification induce aggressive pediatric cancers, the most common of which are solid extracranial tumors in children (neuroblastoma, NB) and malignant pediatric CNS tumors (me...

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Detalles Bibliográficos
Autores principales: Valinciute, Gintvile, Eing, Lorenz, Mihalic, Jeffrey, Casey, Colleen E, Tian, Hua, Adhikari, Bikash, Guiducci, Cristiana, Rountree, Ryan, Grohmann, Christoph, Sridharan, Sangita, Lu, Ya-Wen, Vezina-Dawod, Simon, Wegrzyniak, Eric, Chaterjee, Abhinav, Hansen, Gwenn M, Maris, John M, Mossé, Yael P, Eilers, Martin, Wolf, Elmar, Roussel, Martine F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Other (Not Fitting in any Other Category) - OTHR
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260097/
http://dx.doi.org/10.1093/neuonc/noad073.284

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260097/
http://dx.doi.org/10.1093/neuonc/noad073.284

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