XRT-06. RAPID PTEFB-DEPENDENT TRANSCRIPTIONAL REORGANIZATION UNDERPINS THE GLIOMA ADAPTIVE RESPONSE TO RADIOTHERAPY

Dynamic regulation of gene expression is fundamental for cellular adaptation to exogenous stressors. PTEFb-mediated pause-release of RNA polymerase II (Pol II) is a conserved regulatory mechanism for synchronous transcriptional induction in response to heat shock, but this pro-survival role has not...

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Detalles Bibliográficos
Autores principales: Walker, Faye, Sobral, Lays Martin, Danis, Etienne, Sanford, Bridget, Balakrishnan, Ilango, Wang, Dong, Pierce, Angela, Karam, Sana, Serkova, Natalie, Foreman, Nicholas, Venkataraman, Sujatha, Dowell, Robin, Vibhakar, Rajeev, Dahl, Nathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Radiation Oncology - XRT
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260099/
http://dx.doi.org/10.1093/neuonc/noad073.302

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