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MDB-27. A PRO-DRUG OF TRIPTOLIDE IN CLINICAL DEVELOPMENT ATTENUATES HIGH-RISK MEDULLOBLASTOMA GROWTH
Medulloblastoma (MB), the most common malignant brain tumor of childhood, is currently classified in four major subgroups. A natural compound used in Chinese medicine for centuries, triptolide, has been shown to have a potent antitumor activity, and the efficacy of one of its derivatives is being ev...
Autores principales: | Rodriguez-Blanco, Jezabel, Salvador, April, Suter, Robert, Palomo-Caturla, Isabel, Viera, Megan, Nienhius, Ashley Metts, Ayad, Nagi, Robbins, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260121/ http://dx.doi.org/10.1093/neuonc/noad073.259 |
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