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MDB-33. REST AND USP37 CONTROL THE MTORC1-AUTOPHAGY AXIS IN MEDULLOBLASTOMA BY REGULATING RAPTOR DEGRADATION

The RE1 Silencing Transcription Factor (REST) is a repressor of neurogenesis. Its expression is elevated in the pediatric brain tumor medulloblastoma (MB) and correlates with poor patient prognosis. RNAseq analyses of MB tumors identified significant differences in the expression of genes associated...

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Detalles Bibliográficos
Autores principales:	Cheng, Donghang, Singh, Ashutosh, Haltom, Amanda R, Zheng, Yan, Sharma, Ajay, Lopez, Mariana, Gordon, Nancy, Gopalakrishnan, Vidya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2023
Materias:	Final Category: Medulloblastomas - MDB
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260137/ http://dx.doi.org/10.1093/neuonc/noad073.265

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