IMMU-06. SYSTEMIC MRNA VACCINES RESET IMMUNOGENICITY AGAINST DIFFUSE MIDLINE GLIOMA

BACKGROUND: DIPG remains a uniformly fatal disease in dire need of new therapies. There are currently no systemic therapies with proven efficacy against these tumors. To overcome these barriers, we developed a systemic mRNA lipid particle (LP) vaccine that localizes to tumors and reticuloendothelial...

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Detalles Bibliográficos
Autores principales: McGuiness, James, Weidert, Frances, DeVries, Anna, Ligon, John, Zhang, Dingpeng, Von Roemeling, Christina, Grippin, Adam, Karachi, Aida, Qdaisat, Sadeem, Thomas, Nagheme, Castillo, Paul, Huang, Jianping, Silver, Natalie, Rahman, Maryam, Hwang, Eugene, Mitchell, Duane, Mendez-Gomez, Hector, Sayour, Elias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Immunology/Immunotherapy - IMMU
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260155/
http://dx.doi.org/10.1093/neuonc/noad073.193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260155/
http://dx.doi.org/10.1093/neuonc/noad073.193

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