HGG-05. PERTURBING GABAERGIC NEURONAL LINEAGE IN DIFFUSE HEMISPHERIC GLIOMA, H3G34-MUTANT, HIGHLIGHTS CDK6 AS A CLINICALLY ACTIONABLE TARGET

Diffuse hemispheric gliomas, H3G34R/V-mutant (DHG-H3G34), are uniformly lethal malignancies with currently no targeted therapies available. They exclusively occur in the cerebral hemispheres of adolescents and young adults, and have been linked to a distinct interneuronal lineage of origin. The deve...

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Detalles Bibliográficos
Autores principales: Liu, Ilon, Cruzeiro, Gustavo Alencastro Veiga, Bjerke, Lynn, Rogers, Rebecca, Grabovska, Yura, Beck, Alexander, Mackay, Alan, Barron, Tara, Hack, Olivia, Quezada, Michael, Molinari, Valeria, Shaw, McKenzie, Temelso, Sara, Raynaud, Florence, Ruddle, Ruth, Panditharatna, Eshini, Englinger, Bernhard, Mire, Hafsa, Jiang, Li, Silva, Andrezza Do Nascimento, LaBelle, Jenna, Haase, Rebecca, Rozowsky, Jacob, Nguyen, Quang-De, Pericoli, Giulia, Madlener, Sibylle, Mayr, Lisa, Dorfer, Christian, Geyeregger, Rene, Ricken, Gerda, Ligon, Keith, Alexandrescu, Sanda, Agnihotri, Sameer, Eisenstat, David, Carceller, Fernando, Stapleton, Simon, Bleil, Cristina, Mastronuzzi, Angela, Cole, Kristina, Waanders, Angela, Carcaboso, Angel Montero, Schüller, Ulrich, Vinci, Maria, Hargrave, Darren, Haberler, Christine, Slavc, Irene, Gojo, Johannes, Monje, Michelle, Jones, Chris, Filbin, Mariella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: High Grade Glioma/Gliomatosis Cerebri - HGG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260163/
http://dx.doi.org/10.1093/neuonc/noad073.154

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