MDB-07. MYC AND TGFΒ PROMOTE GROUP 3 MEDULLOBLASTOMA TUMOR RESISTANCE THROUGH DEREGULATION OF KDM2B TARGETS

Medulloblastoma (MB) is one of the most prevalent malignant brain tumors in children, with tremendous cognitive and neuroendocrine disability among survivors. Group 3 (G3) MBs have poor overall survival at <50%, few recurrent mutations, higher frequency of metastasis, and no targeted therapies. A...

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Detalles Bibliográficos
Autores principales: Qadeer, Zulekha, Westelman, Samantha, Johnson, Mackenzie, Grele, Shane, Hou, Elise, Hendrikse, Liam, Wang, Linyu, Husain, Sarah, Beytagh, Mary Clare, Schmidt, Christin, Huang, Miller, Taylor, Michael, Weiss, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Medulloblastomas - MDB
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260175/
http://dx.doi.org/10.1093/neuonc/noad073.240

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