DIPG-20. DELINEATING MEDIATORS OF ONCOGENESIS IN FOXR2-EXPRESSING DIFFUSE MIDLINE GLIOMAS

BACKGROUND: Diffuse midline gliomas (DMGs) are a universally fatal brain tumor of childhood. While histone mutations are a critical tumor initiating event, they are insufficient to drive gliomagenesis. Histone mutations co-occur with somatic alterations in other pathways including TP53, MAPK, and MY...

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Autores principales: Tsai, Jessica, Cejas, Paloma, Coppola, Marissa, Wang, Dayle, Patel, Smruti, Wu, David, Arounleut, Phonepasong, Wei, Xin, Zhou, Ningxuan, Syamala, Sudeepa, Dubois, Frank, Pelton, Kristine, Vogelzang, Jayne, Sousa, Cecilia, Baguette, Audrey, Chen, Xiaolong, Condurat, Alexandra, Dixon-Clarke, Sarah, Zhou, Kevin, Lu, Sophie, Gonzalez, Elizabeth, Chacon, Madison, Digiacomo, Jeromy, Kumbhani, Rushil, Novikov, Dana, Tsoli, Maria, Ziegler, David, Dirksen, Uta, Jager, Natalie, Balsubramanian, Gnana Prakash, Kramm, Christof, Nathrath, Michaela, Bielack, Stefan, Baker, Suzanne, Zhang, Jinghui, McFarland, James, Getz, Gad, Aguet, Francois, Jabado, Nada, Witt, Olaf, Pfister, Stefan, Ligon, Keith, Hovestadt, Volker, Kleinman, Claudia, Long, Henry, Jones, David, Bandopadhayay, Pratiti, Phoenix, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Final Category: Diffuse Intrinsic Pontine Glioma/Diffuse Midline Gliomas - DPIG
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260201/
http://dx.doi.org/10.1093/neuonc/noad073.067

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