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Concurrent dose-finding of a novel cancer drug with and without a second agent

INTRODUCTION: More complex research questions are being posed in early-phase oncology clinical trials, necessitating design strategies tailored to contemporary study objectives. This paper describes the proposed design of a Phase I trial concurrently evaluating the safety of a hematopoietic progenit...

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Detalles Bibliográficos
Autores principales: Wages, Nolan A., Saleh, Ramy R., Braun, Thomas M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260343/
https://www.ncbi.nlm.nih.gov/pubmed/37313388
http://dx.doi.org/10.1017/cts.2023.542