Gene expression in African Americans, Puerto Ricans and Mexican Americans reveals ancestry-specific patterns of genetic architecture

We explored ancestry-related differences in the genetic architecture of whole-blood gene expression using whole-genome and RNA sequencing data from 2,733 African Americans, Puerto Ricans and Mexican Americans. We found that heritability of gene expression significantly increased with greater proport...

Descripción completa

Detalles Bibliográficos
Autores principales: Kachuri, Linda, Mak, Angel C. Y., Hu, Donglei, Eng, Celeste, Huntsman, Scott, Elhawary, Jennifer R., Gupta, Namrata, Gabriel, Stacey, Xiao, Shujie, Keys, Kevin L., Oni-Orisan, Akinyemi, Rodríguez-Santana, José R., LeNoir, Michael A., Borrell, Luisa N., Zaitlen, Noah A., Williams, L. Keoki, Gignoux, Christopher R., Burchard, Esteban González, Ziv, Elad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260401/
https://www.ncbi.nlm.nih.gov/pubmed/37231098
http://dx.doi.org/10.1038/s41588-023-01377-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260401/
https://www.ncbi.nlm.nih.gov/pubmed/37231098
http://dx.doi.org/10.1038/s41588-023-01377-z

Ejemplares similares