Mapping interindividual dynamics of innate immune response at single-cell resolution

Common genetic variants across individuals modulate the cellular response to pathogens and are implicated in diverse immune pathologies, yet how they dynamically alter the response upon infection is not well understood. Here, we triggered antiviral responses in human fibroblasts from 68 healthy dono...

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Detalles Bibliográficos
Autores principales: Kumasaka, Natsuhiko, Rostom, Raghd, Huang, Ni, Polanski, Krzysztof, Meyer, Kerstin B., Patel, Sharad, Boyd, Rachel, Gomez, Celine, Barnett, Sam N., Panousis, Nikolaos I., Schwartzentruber, Jeremy, Ghoussaini, Maya, Lyons, Paul A., Calero-Nieto, Fernando J., Göttgens, Berthold, Barnes, Josephine L., Worlock, Kaylee B., Yoshida, Masahiro, Nikolić, Marko Z., Stephenson, Emily, Reynolds, Gary, Haniffa, Muzlifah, Marioni, John C., Stegle, Oliver, Hagai, Tzachi, Teichmann, Sarah A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Technical Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260404/
https://www.ncbi.nlm.nih.gov/pubmed/37308670
http://dx.doi.org/10.1038/s41588-023-01421-y

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