Correlations between pathogenic variants in DNA repair genes and anticancer treatment efficacy in stage IV non‐small cell lung cancer: A large real‐world cohort and review of the literature

BACKGROUND: Mutations in genes involved in DNA damage repair (DDR), a hallmark of cancer, are associated with increased cancer cell sensitivity to certain therapies. This study sought to evaluate the association of DDR pathogenic variants with treatment efficacy in patients with advanced non‐small c...

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Detalles Bibliográficos
Autores principales: Averbuch, Itamar, Tschernichovsky, Roi, Icht, Oded, Goldstein, Daniel A., Mutai, Raz, Dudnik, Elizabeth, Rotem, Ofer, Peled, Nir, Allen, Aaron M., Laufer‐Geva, Smadar, Goldberg, Yael, Zer, Alona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260479/
https://www.ncbi.nlm.nih.gov/pubmed/37095004
http://dx.doi.org/10.1111/1759-7714.14902

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