Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma

The optimal approach to locally advanced head and neck squamous cell carcinoma (LAHNSCC) treatment remains controversial. For non-resectable LAHNSCC, the clinical interest of induction chemotherapy followed by concurrent chemoradiotherapy (CCRT) or radiotherapy has been questioned. With the approval...

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Detalles Bibliográficos
Autores principales: Zheng, Shuwen, Feng, Yumei, Li, Chan, Zhang, Jie, Xie, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260727/
https://www.ncbi.nlm.nih.gov/pubmed/36943658
http://dx.doi.org/10.1007/s40487-023-00226-7
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author Zheng, Shuwen
Feng, Yumei
Li, Chan
Zhang, Jie
Xie, Ke
author_facet Zheng, Shuwen
Feng, Yumei
Li, Chan
Zhang, Jie
Xie, Ke
author_sort Zheng, Shuwen
collection PubMed
description The optimal approach to locally advanced head and neck squamous cell carcinoma (LAHNSCC) treatment remains controversial. For non-resectable LAHNSCC, the clinical interest of induction chemotherapy followed by concurrent chemoradiotherapy (CCRT) or radiotherapy has been questioned. With the approval of immunotherapy and targeted therapy for this disease, treatment options have become more complex. Although new trial data have appeared every year, the results are still inconclusive. In this review, we provide readers with information on new strategies for LAHNSCC induction therapy, which will facilitate evidence-based decision making in LAHNSCC treatment.
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spelling pubmed-102607272023-06-15 Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma Zheng, Shuwen Feng, Yumei Li, Chan Zhang, Jie Xie, Ke Oncol Ther Review The optimal approach to locally advanced head and neck squamous cell carcinoma (LAHNSCC) treatment remains controversial. For non-resectable LAHNSCC, the clinical interest of induction chemotherapy followed by concurrent chemoradiotherapy (CCRT) or radiotherapy has been questioned. With the approval of immunotherapy and targeted therapy for this disease, treatment options have become more complex. Although new trial data have appeared every year, the results are still inconclusive. In this review, we provide readers with information on new strategies for LAHNSCC induction therapy, which will facilitate evidence-based decision making in LAHNSCC treatment. Springer Healthcare 2023-03-21 /pmc/articles/PMC10260727/ /pubmed/36943658 http://dx.doi.org/10.1007/s40487-023-00226-7 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by-nc/4.0/Open AccessThis article is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License, which permits any non-commercial use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Review
Zheng, Shuwen
Feng, Yumei
Li, Chan
Zhang, Jie
Xie, Ke
Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
title Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
title_full Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
title_fullStr Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
title_full_unstemmed Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
title_short Induction Therapy for Locally Advanced Head and Neck Squamous Cell Carcinoma
title_sort induction therapy for locally advanced head and neck squamous cell carcinoma
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10260727/
https://www.ncbi.nlm.nih.gov/pubmed/36943658
http://dx.doi.org/10.1007/s40487-023-00226-7
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