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Disparity in the use of Alzheimer's disease treatment in Southern Brazil

Alzheimer's disease (AD) treatment is freely available in the Brazilian public health system. However, the prescription pattern and its associated factors have been poorly studied in our country. We reviewed all granted requests for AD treatment in the public health system in October 2021 in th...

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Autores principales: De Marco, Maisa, Brandi, Ana Laura, Bieger, Andrei, Krug, Bárbara, Camozzato, Analuiza, Picon, Paulo D., Chaves, Marcia Lorena Fagundes, Castilhos, Raphael Machado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261112/
https://www.ncbi.nlm.nih.gov/pubmed/37308535
http://dx.doi.org/10.1038/s41598-023-36604-4
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author De Marco, Maisa
Brandi, Ana Laura
Bieger, Andrei
Krug, Bárbara
Camozzato, Analuiza
Picon, Paulo D.
Chaves, Marcia Lorena Fagundes
Castilhos, Raphael Machado
author_facet De Marco, Maisa
Brandi, Ana Laura
Bieger, Andrei
Krug, Bárbara
Camozzato, Analuiza
Picon, Paulo D.
Chaves, Marcia Lorena Fagundes
Castilhos, Raphael Machado
author_sort De Marco, Maisa
collection PubMed
description Alzheimer's disease (AD) treatment is freely available in the Brazilian public health system. However, the prescription pattern and its associated factors have been poorly studied in our country. We reviewed all granted requests for AD treatment in the public health system in October 2021 in the Rio Grande do Sul (RS) state, Southern Brazil. We performed a spatial autocorrelation analysis with the population-adjusted patients receiving any AD medication as the outcome and correlated it with several socioeconomic variables. 2382 patients with AD were being treated during the period analyzed. The distribution of the outcome variable was not random (Moran's I 0.17562, P <.0001), with the most developed regions having a higher number of patients/100,000 receiving any AD medication. We show that although AD medications are available through the public health system, there is a clear disparity between regions of RS state. Factors related to socioeconomic development partly explain this finding.
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spelling pubmed-102611122023-06-15 Disparity in the use of Alzheimer's disease treatment in Southern Brazil De Marco, Maisa Brandi, Ana Laura Bieger, Andrei Krug, Bárbara Camozzato, Analuiza Picon, Paulo D. Chaves, Marcia Lorena Fagundes Castilhos, Raphael Machado Sci Rep Article Alzheimer's disease (AD) treatment is freely available in the Brazilian public health system. However, the prescription pattern and its associated factors have been poorly studied in our country. We reviewed all granted requests for AD treatment in the public health system in October 2021 in the Rio Grande do Sul (RS) state, Southern Brazil. We performed a spatial autocorrelation analysis with the population-adjusted patients receiving any AD medication as the outcome and correlated it with several socioeconomic variables. 2382 patients with AD were being treated during the period analyzed. The distribution of the outcome variable was not random (Moran's I 0.17562, P <.0001), with the most developed regions having a higher number of patients/100,000 receiving any AD medication. We show that although AD medications are available through the public health system, there is a clear disparity between regions of RS state. Factors related to socioeconomic development partly explain this finding. Nature Publishing Group UK 2023-06-12 /pmc/articles/PMC10261112/ /pubmed/37308535 http://dx.doi.org/10.1038/s41598-023-36604-4 Text en © The Author(s) 2023, corrected publication 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
De Marco, Maisa
Brandi, Ana Laura
Bieger, Andrei
Krug, Bárbara
Camozzato, Analuiza
Picon, Paulo D.
Chaves, Marcia Lorena Fagundes
Castilhos, Raphael Machado
Disparity in the use of Alzheimer's disease treatment in Southern Brazil
title Disparity in the use of Alzheimer's disease treatment in Southern Brazil
title_full Disparity in the use of Alzheimer's disease treatment in Southern Brazil
title_fullStr Disparity in the use of Alzheimer's disease treatment in Southern Brazil
title_full_unstemmed Disparity in the use of Alzheimer's disease treatment in Southern Brazil
title_short Disparity in the use of Alzheimer's disease treatment in Southern Brazil
title_sort disparity in the use of alzheimer's disease treatment in southern brazil
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261112/
https://www.ncbi.nlm.nih.gov/pubmed/37308535
http://dx.doi.org/10.1038/s41598-023-36604-4
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