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Common genetic variants contribute to heritability of age at onset of schizophrenia

Schizophrenia (SCZ) is a complex disorder that typically arises in late adolescence or early adulthood. Age at onset (AAO) of SCZ is associated with long-term outcomes of the disease. We explored the genetic architecture of AAO with a genome-wide association study (GWAS), heritability, polygenic ris...

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Detalles Bibliográficos
Autores principales: Sada-Fuente, Ester, Aranda, Selena, Papiol, Sergi, Heilbronner, Urs, Moltó, María Dolores, Aguilar, Eduardo J., González-Peñas, Javier, Andreu-Bernabeu, Álvaro, Arango, Celso, Crespo-Facorro, Benedicto, González-Pinto, Ana, Fañanás, Lourdes, Arias, Barbara, Bobes, Julio, Costas, Javier, Martorell, Lourdes, Schulze, Thomas G., Kalman, Janos L., Vilella, Elisabet, Muntané, Gerard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261125/
https://www.ncbi.nlm.nih.gov/pubmed/37308478
http://dx.doi.org/10.1038/s41398-023-02508-0

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