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Relationship of paroxysmal nocturnal hemoglobinuria (PNH) granulocyte clone size to disease burden and risk of major vascular events in untreated patients: results from the International PNH Registry

Paroxysmal nocturnal hemoglobinuria (PNH) is caused by acquired gene mutations resulting in deficiency of glycosylphosphatidylinositol (GPI)–anchored complement regulatory proteins on the surface of blood cells, leading to terminal complement–mediated intravascular hemolysis and increased risk of ma...

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Detalles Bibliográficos
Autores principales:	Dingli, David, Maciejewski, Jaroslaw P., Larratt, Loree, Go, Ronald S., Höchsmann, Britta, Zu, Ke, Gustovic, Philippe, Kulagin, Alexander D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2023
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261189/ https://www.ncbi.nlm.nih.gov/pubmed/37199789 http://dx.doi.org/10.1007/s00277-023-05269-4

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