Tau seeds occur before earliest Alzheimer’s changes and are prevalent across neurodegenerative diseases

Tau neurofibrillary tangles are a hallmark of Alzheimer’s disease neuropathological change. However, it remains largely unclear how distinctive Alzheimer’s disease tau seeds (i.e. 3R/4R) correlate with histological indicators of tau accumulation. Furthermore, AD tau co-pathology is thought to influe...

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Detalles Bibliográficos
Autores principales: Manca, Matteo, Standke, Heidi G., Browne, Danielle F., Huntley, Mikayla L., Thomas, Olivia R., Orrú, Christina D., Hughson, Andrew G., Kim, Yongya, Zhang, Jing, Tatsuoka, Curtis, Zhu, Xiongwei, Hiniker, Annie, Coughlin, David G., Galasko, Douglas, Kraus, Allison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261243/
https://www.ncbi.nlm.nih.gov/pubmed/37154939
http://dx.doi.org/10.1007/s00401-023-02574-0

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