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The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis

Purslane (Portulaca oleracea L.) is a herbal remedy with wide range of pharmaceutic properties. Although the beneficial effect of purslane on the treatment of Type 2 Diabetes Mellitus (T2DM) has been shown, there is an inconsistency among the results of previous studies. Therefore, this study is aim...

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Autores principales: Jafari, Naser, Shoaibinobarian, Nargeskhatoon, Dehghani, Azadeh, Rad, Amirhosein, Mirmohammadali, Seyedeh Nooshan, Alaeian, Mohammad Javad, Hamedi, Yasaman, Zamani, Mohamad, Goudarzi, Mohammad Ali, Asbaghi, Omid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261734/
https://www.ncbi.nlm.nih.gov/pubmed/37324837
http://dx.doi.org/10.1002/fsn3.3311
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author Jafari, Naser
Shoaibinobarian, Nargeskhatoon
Dehghani, Azadeh
Rad, Amirhosein
Mirmohammadali, Seyedeh Nooshan
Alaeian, Mohammad Javad
Hamedi, Yasaman
Zamani, Mohamad
Goudarzi, Mohammad Ali
Asbaghi, Omid
author_facet Jafari, Naser
Shoaibinobarian, Nargeskhatoon
Dehghani, Azadeh
Rad, Amirhosein
Mirmohammadali, Seyedeh Nooshan
Alaeian, Mohammad Javad
Hamedi, Yasaman
Zamani, Mohamad
Goudarzi, Mohammad Ali
Asbaghi, Omid
author_sort Jafari, Naser
collection PubMed
description Purslane (Portulaca oleracea L.) is a herbal remedy with wide range of pharmaceutic properties. Although the beneficial effect of purslane on the treatment of Type 2 Diabetes Mellitus (T2DM) has been shown, there is an inconsistency among the results of previous studies. Therefore, this study is aimed at conducting a systematic review and meta‐analysis on the effect of purslane on glycemic profile and oxidative stress markers. A systematic search was performed in the Scopus, Web of science, PubMed and the Cochrane Library to find articles related to the effect of the purslane on Malondialdehyde (MDA) and Total Antioxidant Capacity (TAC), Fasting Blood Sugar (FBS), Hemoglobin A1c (HbA1c), insulin resistance, Homeostatic Model Assessment for Insulin Resistance (HOMA‐IR) up to September 2022. Among the 611 initial studies that were identified from searching electronic databases, 16 Randomized Clinical Trials (RCTs) involving 1122 participants (557 cases and 565 controls) were included for data analysis. The results of random‐effects modeling demonstrated that purslane consumption significantly reduced FBS (p < .001), MDA (p < .001) and increased TAC (p < .001). However, purslane consumption did not affect HbA1c (p < .109), fasting insulin (p = .298) and HOMA‐IR (p = .382). Meta‐analyses were performed using both the random‐ and fixed‐effects model where appropriate, and I (2) index was used to evaluate the heterogeneity. This meta‐analysis study suggests that purslane has beneficial effects on oxidative stress markers and glycemic parameter. Therefore, it may be a promising adjuvant therapy in T2DM because of its benefits and negligible adverse effects.
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spelling pubmed-102617342023-06-15 The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis Jafari, Naser Shoaibinobarian, Nargeskhatoon Dehghani, Azadeh Rad, Amirhosein Mirmohammadali, Seyedeh Nooshan Alaeian, Mohammad Javad Hamedi, Yasaman Zamani, Mohamad Goudarzi, Mohammad Ali Asbaghi, Omid Food Sci Nutr Reviews Purslane (Portulaca oleracea L.) is a herbal remedy with wide range of pharmaceutic properties. Although the beneficial effect of purslane on the treatment of Type 2 Diabetes Mellitus (T2DM) has been shown, there is an inconsistency among the results of previous studies. Therefore, this study is aimed at conducting a systematic review and meta‐analysis on the effect of purslane on glycemic profile and oxidative stress markers. A systematic search was performed in the Scopus, Web of science, PubMed and the Cochrane Library to find articles related to the effect of the purslane on Malondialdehyde (MDA) and Total Antioxidant Capacity (TAC), Fasting Blood Sugar (FBS), Hemoglobin A1c (HbA1c), insulin resistance, Homeostatic Model Assessment for Insulin Resistance (HOMA‐IR) up to September 2022. Among the 611 initial studies that were identified from searching electronic databases, 16 Randomized Clinical Trials (RCTs) involving 1122 participants (557 cases and 565 controls) were included for data analysis. The results of random‐effects modeling demonstrated that purslane consumption significantly reduced FBS (p < .001), MDA (p < .001) and increased TAC (p < .001). However, purslane consumption did not affect HbA1c (p < .109), fasting insulin (p = .298) and HOMA‐IR (p = .382). Meta‐analyses were performed using both the random‐ and fixed‐effects model where appropriate, and I (2) index was used to evaluate the heterogeneity. This meta‐analysis study suggests that purslane has beneficial effects on oxidative stress markers and glycemic parameter. Therefore, it may be a promising adjuvant therapy in T2DM because of its benefits and negligible adverse effects. John Wiley and Sons Inc. 2023-03-15 /pmc/articles/PMC10261734/ /pubmed/37324837 http://dx.doi.org/10.1002/fsn3.3311 Text en © 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Jafari, Naser
Shoaibinobarian, Nargeskhatoon
Dehghani, Azadeh
Rad, Amirhosein
Mirmohammadali, Seyedeh Nooshan
Alaeian, Mohammad Javad
Hamedi, Yasaman
Zamani, Mohamad
Goudarzi, Mohammad Ali
Asbaghi, Omid
The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis
title The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis
title_full The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis
title_fullStr The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis
title_full_unstemmed The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis
title_short The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis
title_sort effects of purslane consumption on glycemic control and oxidative stress: a systematic review and dose–response meta‐analysis
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261734/
https://www.ncbi.nlm.nih.gov/pubmed/37324837
http://dx.doi.org/10.1002/fsn3.3311
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