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The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis
Purslane (Portulaca oleracea L.) is a herbal remedy with wide range of pharmaceutic properties. Although the beneficial effect of purslane on the treatment of Type 2 Diabetes Mellitus (T2DM) has been shown, there is an inconsistency among the results of previous studies. Therefore, this study is aim...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261734/ https://www.ncbi.nlm.nih.gov/pubmed/37324837 http://dx.doi.org/10.1002/fsn3.3311 |
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author | Jafari, Naser Shoaibinobarian, Nargeskhatoon Dehghani, Azadeh Rad, Amirhosein Mirmohammadali, Seyedeh Nooshan Alaeian, Mohammad Javad Hamedi, Yasaman Zamani, Mohamad Goudarzi, Mohammad Ali Asbaghi, Omid |
author_facet | Jafari, Naser Shoaibinobarian, Nargeskhatoon Dehghani, Azadeh Rad, Amirhosein Mirmohammadali, Seyedeh Nooshan Alaeian, Mohammad Javad Hamedi, Yasaman Zamani, Mohamad Goudarzi, Mohammad Ali Asbaghi, Omid |
author_sort | Jafari, Naser |
collection | PubMed |
description | Purslane (Portulaca oleracea L.) is a herbal remedy with wide range of pharmaceutic properties. Although the beneficial effect of purslane on the treatment of Type 2 Diabetes Mellitus (T2DM) has been shown, there is an inconsistency among the results of previous studies. Therefore, this study is aimed at conducting a systematic review and meta‐analysis on the effect of purslane on glycemic profile and oxidative stress markers. A systematic search was performed in the Scopus, Web of science, PubMed and the Cochrane Library to find articles related to the effect of the purslane on Malondialdehyde (MDA) and Total Antioxidant Capacity (TAC), Fasting Blood Sugar (FBS), Hemoglobin A1c (HbA1c), insulin resistance, Homeostatic Model Assessment for Insulin Resistance (HOMA‐IR) up to September 2022. Among the 611 initial studies that were identified from searching electronic databases, 16 Randomized Clinical Trials (RCTs) involving 1122 participants (557 cases and 565 controls) were included for data analysis. The results of random‐effects modeling demonstrated that purslane consumption significantly reduced FBS (p < .001), MDA (p < .001) and increased TAC (p < .001). However, purslane consumption did not affect HbA1c (p < .109), fasting insulin (p = .298) and HOMA‐IR (p = .382). Meta‐analyses were performed using both the random‐ and fixed‐effects model where appropriate, and I (2) index was used to evaluate the heterogeneity. This meta‐analysis study suggests that purslane has beneficial effects on oxidative stress markers and glycemic parameter. Therefore, it may be a promising adjuvant therapy in T2DM because of its benefits and negligible adverse effects. |
format | Online Article Text |
id | pubmed-10261734 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-102617342023-06-15 The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis Jafari, Naser Shoaibinobarian, Nargeskhatoon Dehghani, Azadeh Rad, Amirhosein Mirmohammadali, Seyedeh Nooshan Alaeian, Mohammad Javad Hamedi, Yasaman Zamani, Mohamad Goudarzi, Mohammad Ali Asbaghi, Omid Food Sci Nutr Reviews Purslane (Portulaca oleracea L.) is a herbal remedy with wide range of pharmaceutic properties. Although the beneficial effect of purslane on the treatment of Type 2 Diabetes Mellitus (T2DM) has been shown, there is an inconsistency among the results of previous studies. Therefore, this study is aimed at conducting a systematic review and meta‐analysis on the effect of purslane on glycemic profile and oxidative stress markers. A systematic search was performed in the Scopus, Web of science, PubMed and the Cochrane Library to find articles related to the effect of the purslane on Malondialdehyde (MDA) and Total Antioxidant Capacity (TAC), Fasting Blood Sugar (FBS), Hemoglobin A1c (HbA1c), insulin resistance, Homeostatic Model Assessment for Insulin Resistance (HOMA‐IR) up to September 2022. Among the 611 initial studies that were identified from searching electronic databases, 16 Randomized Clinical Trials (RCTs) involving 1122 participants (557 cases and 565 controls) were included for data analysis. The results of random‐effects modeling demonstrated that purslane consumption significantly reduced FBS (p < .001), MDA (p < .001) and increased TAC (p < .001). However, purslane consumption did not affect HbA1c (p < .109), fasting insulin (p = .298) and HOMA‐IR (p = .382). Meta‐analyses were performed using both the random‐ and fixed‐effects model where appropriate, and I (2) index was used to evaluate the heterogeneity. This meta‐analysis study suggests that purslane has beneficial effects on oxidative stress markers and glycemic parameter. Therefore, it may be a promising adjuvant therapy in T2DM because of its benefits and negligible adverse effects. John Wiley and Sons Inc. 2023-03-15 /pmc/articles/PMC10261734/ /pubmed/37324837 http://dx.doi.org/10.1002/fsn3.3311 Text en © 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Reviews Jafari, Naser Shoaibinobarian, Nargeskhatoon Dehghani, Azadeh Rad, Amirhosein Mirmohammadali, Seyedeh Nooshan Alaeian, Mohammad Javad Hamedi, Yasaman Zamani, Mohamad Goudarzi, Mohammad Ali Asbaghi, Omid The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis |
title | The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis |
title_full | The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis |
title_fullStr | The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis |
title_full_unstemmed | The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis |
title_short | The effects of purslane consumption on glycemic control and oxidative stress: A systematic review and dose–response meta‐analysis |
title_sort | effects of purslane consumption on glycemic control and oxidative stress: a systematic review and dose–response meta‐analysis |
topic | Reviews |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261734/ https://www.ncbi.nlm.nih.gov/pubmed/37324837 http://dx.doi.org/10.1002/fsn3.3311 |
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