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Vitamin D status among infants and children in Shanghai, China: A hospital‐based study

The variation in vitamin D status is still unclear. We aim to describe the vitamin D status among healthy infants and children in Shanghai (31° N latitude), one of the largest cities in China. We conducted a hospital‐based, 2‐year retrospective observational study and recruited children for health e...

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Autores principales: Wu, Ying, Wang, Fang, Li, Aiguo, Gao, Jiangfang, Li, Bosheng, Sheng, Huiming, Ma, Jun, Liao, Xiang‐Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261785/
https://www.ncbi.nlm.nih.gov/pubmed/37324927
http://dx.doi.org/10.1002/fsn3.3292
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author Wu, Ying
Wang, Fang
Li, Aiguo
Gao, Jiangfang
Li, Bosheng
Sheng, Huiming
Ma, Jun
Liao, Xiang‐Peng
author_facet Wu, Ying
Wang, Fang
Li, Aiguo
Gao, Jiangfang
Li, Bosheng
Sheng, Huiming
Ma, Jun
Liao, Xiang‐Peng
author_sort Wu, Ying
collection PubMed
description The variation in vitamin D status is still unclear. We aim to describe the vitamin D status among healthy infants and children in Shanghai (31° N latitude), one of the largest cities in China. We conducted a hospital‐based, 2‐year retrospective observational study and recruited children for health examination at the Tongren Hospital affiliated with Shanghai Jiao Tong University School of Medicine from January 2019 to December 2020. Serum 25‐hydroxyvitamin D (25(OH)D) levels were measured using an enzyme‐linked immunosorbent assay. A total of 6164 children aged 0–11 years were included. Of these, 94.4% of the serum 25(OH)D measurements at first assessment were within the range of 12–50 ng/mL. The median 25(OH)D level was 31.3 (IQR 25.6, 38.1) ng/mL, the percentages of 25(OH)D < 20 ng/mL and 25(OH)D < 30 ng/mL were 10.0% and 43.8%, respectively. Low vitamin D status (deficiency and insufficiency) differed significantly by age group (infants, toddlers, preschoolers, and schoolers) and seasonality (all p < .001), but not by gender. For the sub‐group (n = 855) of children with repeated assessments, their low 25(OH)D levels increased significantly whether after about a 7‐month (n = 351) or 12‐month (n = 504) interval, and the increments of median 25(OH)D levels were 8.1 ng/mL and 2.1 ng/mL respectively (p < .001). This study documents the vitamin D status in Shanghai, showing that low vitamin D status is common in infants and children and suggesting that the assessment of 25(OH)D level is necessary for individuals who are at risk for deficiency or excess.
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spelling pubmed-102617852023-06-15 Vitamin D status among infants and children in Shanghai, China: A hospital‐based study Wu, Ying Wang, Fang Li, Aiguo Gao, Jiangfang Li, Bosheng Sheng, Huiming Ma, Jun Liao, Xiang‐Peng Food Sci Nutr Original Articles The variation in vitamin D status is still unclear. We aim to describe the vitamin D status among healthy infants and children in Shanghai (31° N latitude), one of the largest cities in China. We conducted a hospital‐based, 2‐year retrospective observational study and recruited children for health examination at the Tongren Hospital affiliated with Shanghai Jiao Tong University School of Medicine from January 2019 to December 2020. Serum 25‐hydroxyvitamin D (25(OH)D) levels were measured using an enzyme‐linked immunosorbent assay. A total of 6164 children aged 0–11 years were included. Of these, 94.4% of the serum 25(OH)D measurements at first assessment were within the range of 12–50 ng/mL. The median 25(OH)D level was 31.3 (IQR 25.6, 38.1) ng/mL, the percentages of 25(OH)D < 20 ng/mL and 25(OH)D < 30 ng/mL were 10.0% and 43.8%, respectively. Low vitamin D status (deficiency and insufficiency) differed significantly by age group (infants, toddlers, preschoolers, and schoolers) and seasonality (all p < .001), but not by gender. For the sub‐group (n = 855) of children with repeated assessments, their low 25(OH)D levels increased significantly whether after about a 7‐month (n = 351) or 12‐month (n = 504) interval, and the increments of median 25(OH)D levels were 8.1 ng/mL and 2.1 ng/mL respectively (p < .001). This study documents the vitamin D status in Shanghai, showing that low vitamin D status is common in infants and children and suggesting that the assessment of 25(OH)D level is necessary for individuals who are at risk for deficiency or excess. John Wiley and Sons Inc. 2023-03-08 /pmc/articles/PMC10261785/ /pubmed/37324927 http://dx.doi.org/10.1002/fsn3.3292 Text en © 2023 The Authors. Food Science & Nutrition published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Wu, Ying
Wang, Fang
Li, Aiguo
Gao, Jiangfang
Li, Bosheng
Sheng, Huiming
Ma, Jun
Liao, Xiang‐Peng
Vitamin D status among infants and children in Shanghai, China: A hospital‐based study
title Vitamin D status among infants and children in Shanghai, China: A hospital‐based study
title_full Vitamin D status among infants and children in Shanghai, China: A hospital‐based study
title_fullStr Vitamin D status among infants and children in Shanghai, China: A hospital‐based study
title_full_unstemmed Vitamin D status among infants and children in Shanghai, China: A hospital‐based study
title_short Vitamin D status among infants and children in Shanghai, China: A hospital‐based study
title_sort vitamin d status among infants and children in shanghai, china: a hospital‐based study
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261785/
https://www.ncbi.nlm.nih.gov/pubmed/37324927
http://dx.doi.org/10.1002/fsn3.3292
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