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Differentiation of stem cell-derived pancreatic progenitors into insulin-secreting islet clusters in a multiwell-based static 3D culture system

Orbital shaker-based suspension culture systems have been in widespread use for differentiating human pluripotent stem cell (hPSC)-derived pancreatic progenitors toward islet-like clusters during endocrine induction stages. However, reproducibility between experiments is hampered by variable degrees...

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Detalles Bibliográficos
Autores principales: Liang, Shenghui, Zhao, Jia, Baker, Robert K., Tran, Elisa, Zhan, Lisa, Kieffer, Timothy J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261893/
https://www.ncbi.nlm.nih.gov/pubmed/37323565
http://dx.doi.org/10.1016/j.crmeth.2023.100466