Sequence enrichment profiles enable target-agnostic antibody generation for a broad range of antigens

Phenotypic drug discovery (PDD) enables the target-agnostic generation of therapeutic drugs with novel mechanisms of action. However, realizing its full potential for biologics discovery requires new technologies to produce antibodies to all, a priori unknown, disease-associated biomolecules. We pre...

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Detalles Bibliográficos
Autores principales: Mattsson, Jenny, Ljungars, Anne, Carlsson, Anders, Svensson, Carolin, Nilsson, Björn, Ohlin, Mats, Frendéus, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261905/
https://www.ncbi.nlm.nih.gov/pubmed/37323567
http://dx.doi.org/10.1016/j.crmeth.2023.100475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261905/
https://www.ncbi.nlm.nih.gov/pubmed/37323567
http://dx.doi.org/10.1016/j.crmeth.2023.100475

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