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Sequence enrichment profiles enable target-agnostic antibody generation for a broad range of antigens
Phenotypic drug discovery (PDD) enables the target-agnostic generation of therapeutic drugs with novel mechanisms of action. However, realizing its full potential for biologics discovery requires new technologies to produce antibodies to all, a priori unknown, disease-associated biomolecules. We pre...
Autores principales: | Mattsson, Jenny, Ljungars, Anne, Carlsson, Anders, Svensson, Carolin, Nilsson, Björn, Ohlin, Mats, Frendéus, Björn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261905/ https://www.ncbi.nlm.nih.gov/pubmed/37323567 http://dx.doi.org/10.1016/j.crmeth.2023.100475 |
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