Molecular tools unveil distinct waves of ADP-ribosylation during DNA repair

ADP-ribosylation is a complex post-translation modification involved in DNA repair. In a recent Molecular Cell publication, Longarini and colleagues measured ADP-ribosylation dynamics with unprecedented specificity, revealing how the monomeric and polymeric forms of ADP-ribosylation regulate the tim...

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Detalles Bibliográficos
Autores principales: Dasovich, Morgan, Leung, Anthony K.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261921/
https://www.ncbi.nlm.nih.gov/pubmed/37323576
http://dx.doi.org/10.1016/j.crmeth.2023.100484
Descripción
Sumario:ADP-ribosylation is a complex post-translation modification involved in DNA repair. In a recent Molecular Cell publication, Longarini and colleagues measured ADP-ribosylation dynamics with unprecedented specificity, revealing how the monomeric and polymeric forms of ADP-ribosylation regulate the timing of DNA repair events following strand breaks.

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