A closer look at the synapse: dlg1[4K] enables cell-specific visualization of PSD-95/DLG1

The PSD-95 homolog, DLG1, is important for excitatory synapse structure and function throughout the Drosophila nervous system. In this issue of Cell Reports Methods, Parisi et al. present a tool, dlg1[4K], that enables cell-specific DLG1 visualization without altering basal synaptic physiology. This...

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Detalles Bibliográficos
Autores principales: Hendricks, Emily L., Liebl, Faith L.W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10261923/
https://www.ncbi.nlm.nih.gov/pubmed/37323573
http://dx.doi.org/10.1016/j.crmeth.2023.100487
Descripción
Sumario:The PSD-95 homolog, DLG1, is important for excitatory synapse structure and function throughout the Drosophila nervous system. In this issue of Cell Reports Methods, Parisi et al. present a tool, dlg1[4K], that enables cell-specific DLG1 visualization without altering basal synaptic physiology. This tool will potentially enhance our understanding of neuronal development and function in both circuits and individual synapses.

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