Activation of angiotensin-converting enzyme 2 produces an antidepressant-like effect via MAS receptors in mice

Angiotensin (Ang)-converting-enzyme (ACE) 2 converts Ang II into Ang (1–7), which in turn acts on MAS receptors (ACE2/Ang (1–7)/MAS receptors pathway). This pathway has neuroprotective properties, making it a potential therapeutic target for psychiatric disorders such as depression. Thus, we examine...

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Detalles Bibliográficos
Autores principales: Nakagawasai, Osamu, Takahashi, Kohei, Koyama, Taisei, Yamagata, Ryota, Nemoto, Wataru, Tan-No, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262141/
https://www.ncbi.nlm.nih.gov/pubmed/37312182
http://dx.doi.org/10.1186/s13041-023-01040-y

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