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Optical tools for visualizing and controlling human GLP-1 receptor activation with high spatiotemporal resolution

The glucagon-like peptide-1 receptor (GLP1R) is a broadly expressed target of peptide hormones with essential roles in energy and glucose homeostasis, as well as of the blockbuster weight-loss drugs semaglutide and liraglutide. Despite its large clinical relevance, tools to investigate the precise a...

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Detalles Bibliográficos
Autores principales: Duffet, Loïc, Williams, Elyse T, Gresch, Andrea, Chen, Simin, Bhat, Musadiq A, Benke, Dietmar, Hartrampf, Nina, Patriarchi, Tommaso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262203/
https://www.ncbi.nlm.nih.gov/pubmed/37265064
http://dx.doi.org/10.7554/eLife.86628