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Relebactam restores susceptibility of resistant Pseudomonas aeruginosa and Enterobacterales and enhances imipenem activity against chromosomal AmpC-producing species: analysis of global SMART 2018–2020

BACKGROUND: Carbapenem-resistant bacteria are an increasing problem in clinical practice; thus, it is important to identify β-lactamase inhibitors (e.g., relebactam) that can restore carbapenem susceptibility. We report analyses of relebactam enhancement of imipenem activity against both imipenem-no...

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Detalles Bibliográficos
Autores principales: Hilbert, David W., DeRyke, C. Andrew, Motyl, Mary, Hackel, Meredith, Young, Katherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262423/
https://www.ncbi.nlm.nih.gov/pubmed/37312049
http://dx.doi.org/10.1186/s12866-023-02864-3