RNA-based amplicon sequencing is ineffective in measuring metabolic activity in environmental microbial communities

BACKGROUND: Characterization of microbial activity is essential to the understanding of the basic biology of microbial communities, as the function of a microbiome is defined by its biochemically active (“viable”) community members. Current sequence-based technologies can rarely differentiate microb...

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Detalles Bibliográficos
Autores principales: Wang, Ya, Thompson, Kelsey N., Yan, Yan, Short, Meghan I., Zhang, Yancong, Franzosa, Eric A., Shen, Jiaxian, Hartmann, Erica M., Huttenhower, Curtis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262425/
https://www.ncbi.nlm.nih.gov/pubmed/37312147
http://dx.doi.org/10.1186/s40168-022-01449-y

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