HYpofractionated, dose-redistributed RAdiotherapy with protons and photons to combat radiation-induced immunosuppression in head and neck squamous cell carcinoma: study protocol of the phase I HYDRA trial

BACKGROUND: Radiotherapy (RT) is the standard of care for most advanced head and neck squamous cell carcinoma (HNSCC) and results in an unfavorable 5-year overall survival of 40%. Despite strong biological rationale, combining RT with immune checkpoint inhibitors does not result in a survival benefi...

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Detalles Bibliográficos
Autores principales: Elbers, Joris B. W., Gunsch, Pascal A., Debets, Reno, Keereweer, Stijn, van Meerten, Esther, Zindler, Jaap, van Norden, Yvette, Hoogeman, Mischa S., Verduijn, Gerda M., Kroesen, Michiel, Nout, Remi A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262496/
https://www.ncbi.nlm.nih.gov/pubmed/37312053
http://dx.doi.org/10.1186/s12885-023-11031-w

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