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Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models

BACKGROUND: Lysosomal dysfunction has been implicated in a number of neurodegenerative diseases such as Parkinson’s disease (PD). Various molecular, clinical and genetic studies have highlighted a central role of lysosomal pathways and proteins in the pathogenesis of PD. Within PD pathology the syna...

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Detalles Bibliográficos
Autores principales:	Drobny, Alice, Boros, Fanni Annamária, Balta, Denise, Prieto Huarcaya, Susy, Caylioglu, Deniz, Qazi, Niyeti, Vandrey, Julia, Schneider, Yanni, Dobert, Jan Philipp, Pitcairn, Caleb, Mazzulli, Joseph Robert, Zunke, Friederike
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10262594/ https://www.ncbi.nlm.nih.gov/pubmed/37312133 http://dx.doi.org/10.1186/s40035-023-00363-z

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