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Interferons in COVID-19: missed opportunities to prove efficacy in clinical phase III trials?

Interferons were repeatedly used in the therapy of COVID-19 due to their antiviral effects. Three recently published randomized controlled clinical phase III trials (WHO SOLIDARITY, ACTT-3, and SPRINTER) missed their primary objectives, i.e., a significant therapeutic effect of interferons was not d...

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Detalles Bibliográficos
Autores principales: Brzoska, Josef, von Eick, Harald, Hündgen, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263057/
https://www.ncbi.nlm.nih.gov/pubmed/37324124
http://dx.doi.org/10.3389/fmed.2023.1198576