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Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients
CONTEXT: Coronavirus disease 2019 (COVID-19) became a global pandemic that may be associated with significant associated risk factors. AIMS: The aim of this study was to evaluate the factors predisposing risk to death in COVID-19 patients. SETTINGS AND DESIGN: This is a retrospective study that pres...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263073/ https://www.ncbi.nlm.nih.gov/pubmed/37323375 http://dx.doi.org/10.4103/atm.atm_435_22 |
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author | Al Balwi, Wala M. AlGhamdi, Nouf Alshahrani, Reem Abdelrahman, Ihssan H. Mahmoud, Sami Al-Hamad, Ali Al Hamzah, Salma Al Jraid, Fahad Al Turki, Maha Al Balwi, Mohammed A. |
author_facet | Al Balwi, Wala M. AlGhamdi, Nouf Alshahrani, Reem Abdelrahman, Ihssan H. Mahmoud, Sami Al-Hamad, Ali Al Hamzah, Salma Al Jraid, Fahad Al Turki, Maha Al Balwi, Mohammed A. |
author_sort | Al Balwi, Wala M. |
collection | PubMed |
description | CONTEXT: Coronavirus disease 2019 (COVID-19) became a global pandemic that may be associated with significant associated risk factors. AIMS: The aim of this study was to evaluate the factors predisposing risk to death in COVID-19 patients. SETTINGS AND DESIGN: This is a retrospective study that presents the demographic, clinical presentation, and laboratory findings on our patients to determine risk factors contributing to their COVID-19 outcome. METHODS: We used logistic regression (odds ratios) to examine associations between clinical findings and risk of death in COVID-19 patients. All analyses were done using STATA 15. RESULTS: A total of 206 COVID-19 patients were investigated, 28 of them died, and 178 survived. Expired patients were older (74.04 ± 14.45 vs. 55.56 ± 18.41 in those who survived) and mainly of male gender (75% vs. 42% in those who survived). The following factors were strong predictors of death: hypertension (OR: 5.48, 95% CI: 2.10–13.59, P < 0.001), cardiac disease (OR: 5.08, 95% CI: 1.88–13.74, P = 0.001), and hospital admission (OR: 39.75, 95% CI: 5.28–299.12, P < 0.001). In addition, blood group B was more frequent in expired patients (OR: 2.27, 95% CI: 0.78–5.95, P = 0.065). CONCLUSIONS: Our work adds to the current knowledge about the factors predisposing to death in COVID-19 patient. In our cohort, expired patients were of older age and male gender plus they were more likely to have hypertension, cardiac disease, and hospital severe disease. These factors might be used to evaluate risk of death in patients recently diagnosed of COVID-19. |
format | Online Article Text |
id | pubmed-10263073 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-102630732023-06-15 Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients Al Balwi, Wala M. AlGhamdi, Nouf Alshahrani, Reem Abdelrahman, Ihssan H. Mahmoud, Sami Al-Hamad, Ali Al Hamzah, Salma Al Jraid, Fahad Al Turki, Maha Al Balwi, Mohammed A. Ann Thorac Med Original Article CONTEXT: Coronavirus disease 2019 (COVID-19) became a global pandemic that may be associated with significant associated risk factors. AIMS: The aim of this study was to evaluate the factors predisposing risk to death in COVID-19 patients. SETTINGS AND DESIGN: This is a retrospective study that presents the demographic, clinical presentation, and laboratory findings on our patients to determine risk factors contributing to their COVID-19 outcome. METHODS: We used logistic regression (odds ratios) to examine associations between clinical findings and risk of death in COVID-19 patients. All analyses were done using STATA 15. RESULTS: A total of 206 COVID-19 patients were investigated, 28 of them died, and 178 survived. Expired patients were older (74.04 ± 14.45 vs. 55.56 ± 18.41 in those who survived) and mainly of male gender (75% vs. 42% in those who survived). The following factors were strong predictors of death: hypertension (OR: 5.48, 95% CI: 2.10–13.59, P < 0.001), cardiac disease (OR: 5.08, 95% CI: 1.88–13.74, P = 0.001), and hospital admission (OR: 39.75, 95% CI: 5.28–299.12, P < 0.001). In addition, blood group B was more frequent in expired patients (OR: 2.27, 95% CI: 0.78–5.95, P = 0.065). CONCLUSIONS: Our work adds to the current knowledge about the factors predisposing to death in COVID-19 patient. In our cohort, expired patients were of older age and male gender plus they were more likely to have hypertension, cardiac disease, and hospital severe disease. These factors might be used to evaluate risk of death in patients recently diagnosed of COVID-19. Wolters Kluwer - Medknow 2023 2023-04-25 /pmc/articles/PMC10263073/ /pubmed/37323375 http://dx.doi.org/10.4103/atm.atm_435_22 Text en Copyright: © 2023 Annals of Thoracic Medicine https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Al Balwi, Wala M. AlGhamdi, Nouf Alshahrani, Reem Abdelrahman, Ihssan H. Mahmoud, Sami Al-Hamad, Ali Al Hamzah, Salma Al Jraid, Fahad Al Turki, Maha Al Balwi, Mohammed A. Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients |
title | Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients |
title_full | Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients |
title_fullStr | Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients |
title_full_unstemmed | Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients |
title_short | Risk factors predicting disease severity and mortality in coronavirus disease 2019 Saudi Arabian patients |
title_sort | risk factors predicting disease severity and mortality in coronavirus disease 2019 saudi arabian patients |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263073/ https://www.ncbi.nlm.nih.gov/pubmed/37323375 http://dx.doi.org/10.4103/atm.atm_435_22 |
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