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The prognostic impact of subclonal IDH1 mutation in grade 2–4 astrocytomas
BACKGROUND: Isocitrate dehydrogenase (IDH) mutations are thought to represent an early oncogenic event in glioma evolution, found with high penetrance across tumor cells; however, in rare cases, IDH mutation may exist only in a small subset of the total tumor cells (subclonal IDH mutation). METHODS:...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263115/ https://www.ncbi.nlm.nih.gov/pubmed/37324217 http://dx.doi.org/10.1093/noajnl/vdad069 |