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Profilin1 Promotes Renal Tubular Epithelial Cell Apoptosis in Diabetic Nephropathy Through the Hedgehog Signaling Pathway

BACKGROUND: Profilin-1 (PFN1) regulates the dynamic balance of actin and plays an important role in cell functions as a hub protein in signaling molecule interaction networks. Dysregulation of PFN1 is related to pathologic kidney diseases. Diabetic nephropathy (DN) was recently reported as an inflam...

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Detalles Bibliográficos
Autores principales: Mai, Liping, He, Guodong, Chen, Jing, Zhu, Jiening, Chen, Shaoxian, Yang, Hui, Zhang, Mengzhen, Hou, Xinghua, Ke, Miaola, Li, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263159/
https://www.ncbi.nlm.nih.gov/pubmed/37323855
http://dx.doi.org/10.2147/DMSO.S411781