DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner

Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further our understanding of Coronavirus Disease 2019 (COVID-19). We previously performed a genome-wide CRISPR/Cas9 screen to identify proviral host fa...

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Detalles Bibliográficos
Autores principales: Strine, Madison S., Cai, Wesley L., Wei, Jin, Alfajaro, Mia Madel, Filler, Renata B., Biering, Scott B., Sarnik, Sylvia, Chow, Ryan D., Patil, Ajinkya, Cervantes, Kasey S., Collings, Clayton K., DeWeirdt, Peter C., Hanna, Ruth E., Schofield, Kevin, Hulme, Christopher, Konermann, Silvana, Doench, John G., Hsu, Patrick D., Kadoch, Cigall, Yan, Qin, Wilen, Craig B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263356/
https://www.ncbi.nlm.nih.gov/pubmed/37310920
http://dx.doi.org/10.1371/journal.pbio.3002097

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