Identification of orphan histidine kinases that impact sporulation and enterotoxin production by Clostridium perfringens type F strain SM101 in a pathophysiologically-relevant ex vivo mouse intestinal contents model

When causing food poisoning or antibiotic-associated diarrhea, Clostridium perfringens type F strains must sporulate to produce C. perfringens enterotoxin (CPE) in the intestines. C. perfringens is thought to use some of its seven annotated orphan histidine kinases to phosphorylate Spo0A and initiat...

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Detalles Bibliográficos
Autores principales: Mehdizadeh Gohari, Iman, Li, Jihong, Navarro, Mauricio A., Mendonça, Fábio S., Uzal, Francisco A., McClane, Bruce A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10263361/
https://www.ncbi.nlm.nih.gov/pubmed/37262083
http://dx.doi.org/10.1371/journal.ppat.1011429

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