In vivo development of immune tissue in human intestinal organoids transplanted into humanized mice

Human intestinal organoids (HIOs) derived from pluripotent stem cells provide a valuable model for investigating human intestinal organogenesis and physiology, but they lack the immune components required to fully recapitulate the complexity of human intestinal biology and diseases. To address this...

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Detalles Bibliográficos
Autores principales: Bouffi, Carine, Wikenheiser-Brokamp, Kathryn A., Chaturvedi, Praneet, Sundaram, Nambirajan, Goddard, Gillian R., Wunderlich, Mark, Brown, Nicole E., Staab, Janet F., Latanich, Rachel, Zachos, Nicholas C., Holloway, Emily M., Mahe, Maxime M., Poling, Holly M., Vales, Simon, Fisher, Garrett W., Spence, Jason R., Mulloy, James C., Zorn, Aaron M., Wells, James M., Helmrath, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264243/
https://www.ncbi.nlm.nih.gov/pubmed/36702898
http://dx.doi.org/10.1038/s41587-022-01558-x

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