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Multimodal chromatin profiling using nanobody-based single-cell CUT&Tag

Probing histone modifications at a single-cell level in thousands of cells has been enabled by technologies such as single-cell CUT&Tag. Here we describe nano-CUT&Tag (nano-CT), which allows simultaneous mapping of up to three epigenomic modalities at single-cell resolution using nanobody-Tn...

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Detalles Bibliográficos
Autores principales: Bartosovic, Marek, Castelo-Branco, Gonçalo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264246/
https://www.ncbi.nlm.nih.gov/pubmed/36536148
http://dx.doi.org/10.1038/s41587-022-01535-4