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Alanine-based spacers promote an efficient antigen processing and presentation in neoantigen polypeptide vaccines

Neoantigens are tumor-specific antigens that are mostly particular for each patient. Since the immune system is able to mount a specific immune response against these neoantigens, they are a promising tool for the development of therapeutic personalized cancer vaccines. Neoantigens must be presented...

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Detalles Bibliográficos
Autores principales: Aguilar-Gurrieri, Carmen, Barajas, Ana, Rovirosa, Carla, Ortiz, Raquel, Urrea, Victor, de la Iglesia, Nuria, Clotet, Bonaventura, Blanco, Julià, Carrillo, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264286/
https://www.ncbi.nlm.nih.gov/pubmed/36820900
http://dx.doi.org/10.1007/s00262-023-03409-3