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Pacpaint: a histology-based deep learning model uncovers the extensive intratumor molecular heterogeneity of pancreatic adenocarcinoma

Two tumor (Classical/Basal) and stroma (Inactive/active) subtypes of Pancreatic adenocarcinoma (PDAC) with prognostic and theragnostic implications have been described. These molecular subtypes were defined by RNAseq, a costly technique sensitive to sample quality and cellularity, not used in routin...

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Detalles Bibliográficos
Autores principales: Saillard, Charlie, Delecourt, Flore, Schmauch, Benoit, Moindrot, Olivier, Svrcek, Magali, Bardier-Dupas, Armelle, Emile, Jean Francois, Ayadi, Mira, Rebours, Vinciane, de Mestier, Louis, Hammel, Pascal, Neuzillet, Cindy, Bachet, Jean Baptiste, Iovanna, Juan, Dusetti, Nelson, Blum, Yuna, Richard, Magali, Kermezli, Yasmina, Paradis, Valerie, Zaslavskiy, Mikhail, Courtiol, Pierre, Kamoun, Aurelie, Nicolle, Remy, Cros, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264377/
https://www.ncbi.nlm.nih.gov/pubmed/37311751
http://dx.doi.org/10.1038/s41467-023-39026-y

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