Establishment of a novel NFAT-GFP reporter platform useful for the functional avidity maturation of HLA class II-restricted TCRs

CD4(+) T cells that recognize antigenic peptides presented on HLA class II are essential for inducing an optimal anti-tumor immune response, and adoptive transfer of tumor antigen-specific TCR-transduced CD4(+) T cells with high responsiveness against tumor is a promising strategy for cancer treatme...

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Detalles Bibliográficos
Autores principales: Fujiki, Fumihiro, Morimoto, Soyoko, Nishida, Yuya, Tanii, Satoe, Aoyama, Nao, Inatome, Miki, Inoue, Kento, Katsuhara, Akiko, Nakajima, Hiroko, Nakata, Jun, Nishida, Sumiyuki, Tsuboi, Akihiro, Oka, Yoshihiro, Oji, Yusuke, Sogo, Shinji, Sugiyama, Haruo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264488/
https://www.ncbi.nlm.nih.gov/pubmed/36939853
http://dx.doi.org/10.1007/s00262-023-03420-8

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