BTLA dysregulation correlates with poor outcome and diminished T cell-mediated antitumor responses in chronic lymphocytic leukemia

Patients with chronic lymphocytic leukemia (CLL) progressively develop marked immunosuppression, dampening innate and adaptive-driven antitumor responses. However, the underlying mechanisms promoting immune exhaustion are largely unknown. Herein, we provide new insights into the role of BTLA/HVEM ax...

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Detalles Bibliográficos
Autores principales: Sordo-Bahamonde, Christian, Lorenzo-Herrero, Seila, Martínez-Pérez, Alejandra, Gonzalez-Rodriguez, Ana P., Payer, Ángel R., González-García, Esther, Aguilar-García, Candelaria, González-Rodríguez, Sara, López-Soto, Alejandro, García-Torre, Alejandra, Gonzalez, Segundo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10264494/
https://www.ncbi.nlm.nih.gov/pubmed/37041226
http://dx.doi.org/10.1007/s00262-023-03435-1

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